| ACROSS |
| 1. | Container for groceries |
| 4. | The 23rd letter of the Hebrew alphabet |
| 7. | First man |
| 11. | Made supply last |
| 13. | Sign of something about to happen |
| 15. | A river of eastern Russia rising near Lake Baikal and flowing about 4,296 km (2,670 mi) northeast and north to the Laptev Sea |
| 16. | Grandmother |
| 17. | Baby powder |
| 18. | A male red deer |
| 19. | Nucleic acid that carries the genetic information in the cell |
| 22. | Brine-cured salmon |
| 24. | Biblical high priest |
| 25. | Mouth edge |
| 28. | Baseball player Mel |
| 30. | An emergency procedure consisting of external cardiac massage and artificial respiration |
| 32. | Chemical element with properties similar to another |
| 33. | Armed conflict |
| 34. | Atmosphere |
| 35. | Allow |
| 36. | Actor Alda or Thicke |
| 39. | Greek goddess of the dawn |
| 42. | Boat paddle |
| 43. | Part |
| 44. | Zeal |
| 46. | Flaplike covering |
| 48. | Set down |
| 49. | Period |
| 50. | Help |
| 52. | Original Equipment Manufacturer (abbr.) |
| 55. | Italian singer-songwriter Filippo Neviani |
| 56. | Symbol (abbr.) |
| 57. | A group of pheasants |
| 58. | Compass dir. |
| 59. | Direct toward a target or goal |
| 61. | Snakelike fish |
| 64. | Hearing organ |
| 66. | Central Nebraska county |
| 68. | Ancient city of Etruria north of modern-day Rome, Italy |
| 71. | City in the foothills of the Gold Country of California |
| 75. | Against |
| 76. | Inside; within (prefix) |
| 77. | Claim |
| 78. | Inconspicuous attention getter |
| 79. | Spanish title |
| 80. | Monetary unit of Latvia |
|
| DOWN |
| 1. | The inner or back room of a two-room cottage |
| 2. | Alias (abbr.) |
| 3. | A commissioned military rank (abbr.) |
| 4. | Small child |
| 5. | American Medical Association (abbr.) |
| 6. | Not ill |
| 7. | Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord |
| 8. | Prevent from occurring |
| 9. | Of or related to the anus |
| 10. | Sages who visited Jesus and Mary and Joseph |
| 12. | Male parent |
| 14. | Non-commissioned officer (abbr.) |
| 20. | Immediately |
| 21. | _ moment's notice (2 wds.) |
| 23. | One more than ninety |
| 25. | _ and Stitch |
| 26. | Standard of perfection |
| 27. | _ dish (used to culture cells) |
| 29. | Drop behind |
| 31. | Before (prefix) |
| 34. | One (Scot) |
| 37. | Flowery wreath |
| 38. | Gambison |
| 40. | Baking chambers |
| 41. | Fathers |
| 43. | Writing tablet |
| 45. | Create |
| 47. | 24 hours |
| 51. | Institute for Media and Entertainment (abbr.) |
| 53. | Sight organ |
| 54. | Master of Engineering Administration (abbr.) |
| 56. | Particles of soot |
| 59. | The opening section of a North Indian classical performance |
| 60. | Charged atoms |
| 62. | First lady |
| 63. | Grant temporary use of |
| 65. | To free from |
| 67. | A group of snakes |
| 69. | A language that is deliberately created for a specific purpose |
| 70. | Electrically charged atom |
| 72. | Lubricate |
| 73. | Basketball assoc. |
| 74. | Eastern Standard Time (abbr.) |