| ACROSS |
| 1. | (botany) Usually underground organ that lacks buds or leaves or nodes |
| 5. | Attempt |
| 8. | First lady |
| 11. | Celtic language |
| 12. | North American Indian people of Ontario, Manitoba, Saskatchewan, and Montana |
| 13. | Electrically charged atom |
| 14. | Rhinal |
| 16. | Sliced desserts |
| 17. | Sigma Iota Epsilon (abbr.) |
| 18. | Nucleic acid that carries the genetic information in the cell |
| 19. | Town in the historic Nashoba Valley of Massachusetts |
| 22. | Higher Education for Development (abbr.) |
| 23. | So be it |
| 24. | Boy, to dad |
| 25. | Make improvements or corrections to |
| 26. | Otherwise |
| 28. | A river of eastern Russia rising near Lake Baikal and flowing about 4,296 km (2,670 mi) northeast and north to the Laptev Sea |
| 30. | Ocean |
| 32. | _ dish (used to culture cells) |
| 34. | Nonscientific branch of learning |
| 35. | Expire |
| 37. | Atmosphere |
| 38. | Singer Mel |
| 41. | Compass dir. |
| 43. | The main thing one is thinking about |
| 44. | Perceives with the eye |
| 45. | Opt |
| 47. | One (Scot) |
| 48. | Create |
| 49. | It is |
| 50. | Unit of force |
| 51. | Expression of pleasure, satisfaction, surprise, or great joy |
| 54. | Black tropical American cuckoo |
| 55. | Hoop that covers a wheel |
| 58. | Evade |
| 60. | Had dinner |
| 61. | Afresh |
| 62. | Not divided or shared with others |
| 63. | Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord |
| 64. | Can I? |
| 65. | Western Russian city on the Oka River south of Moscow |
|
| DOWN |
| 1. | Tear apart |
| 2. | Sorthwest Algerian city |
| 3. | A peak of the Olympus Mountains in northern Greece |
| 4. | Beverage made from leaves |
| 5. | Three (prefix) |
| 6. | Portuguese money of account (variant) |
| 7. | Consenting reply |
| 8. | Austrian city, state capital of Burgenland |
| 9. | Empty area or space |
| 10. | Compass dir. |
| 12. | An emergency procedure consisting of external cardiac massage and artificial respiration |
| 15. | Unable to walk |
| 20. | Monetary units of Japan |
| 21. | Having come or been brought to a conclusion |
| 22. | Opening into or through something |
| 23. | American Medical Association (abbr.) |
| 24. | Simplified Employee Pension (plan) (abbr.) |
| 25. | Pleas |
| 27. | One of the Great Lakes |
| 28. | Monetary unit of Latvia |
| 29. | Greek god of love |
| 31. | The 18th letter of the Arabic alphabet |
| 33. | Retirement account (abbr.) |
| 36. | Foe |
| 39. | Not women's |
| 40. | Compass dir. |
| 42. | Style |
| 43. | Frozen water |
| 46. | Supplemented with great effort |
| 49. | International (abbr.) |
| 50. | Morning condensation |
| 51. | Aroma |
| 52. | Stare |
| 53. | Person who is morally reprehensible |
| 54. | American Automobile Association (abbr.) |
| 55. | Scottish cap |
| 56. | _ tizzy (2 wds.) |
| 57. | Marina Del _, California |
| 59. | Bear (Spanish) |
