| ACROSS |
| 1. | (biochemistry) Long linear polymer of nucleotides found in a cell |
| 4. | The grampus (Milton) |
| 7. | Midwestern state in north central United States in the Great Lakes region |
| 11. | Like (prefix) |
| 13. | Marked by extreme lack of restraint or control |
| 15. | Watch over |
| 16. | Mouths or openings |
| 17. | The name of a Hindu Caste from the southern Indian state of Kerala |
| 18. | Event that recurs at intervals |
| 19. | Federal agency which regulates the release of new foods and health-related products |
| 22. | Zeal |
| 24. | Distress signal |
| 25. | Pass on |
| 28. | Sep. follower |
| 30. | Erode |
| 32. | Everything |
| 33. | Born |
| 34. | Plant excrement |
| 35. | Lower and raise head in agreement |
| 36. | Nuclear Threat Initiatives |
| 39. | Mouth or opening |
| 42. | A saturated hydrocarbon |
| 43. | Elected official of ancient Rome, responsible for public works and games |
| 44. | Institute for Media and Entertainment (abbr.) |
| 46. | Curve |
| 48. | Sacs in ascomycetes in which the sexual spores are formed |
| 49. | A female yak |
| 50. | Atmosphere |
| 52. | Grow older |
| 55. | Sigma Iota Epsilon (abbr.) |
| 56. | And so on (abbr.) |
| 57. | Two (Sp.) |
| 58. | Conclude |
| 59. | Baking dish |
| 61. | Small bed |
| 64. | Original Equipment Manufacturer (abbr.) |
| 66. | In addition |
| 68. | Money forfeited if the accused fails to appear for trial |
| 71. | Am not, is not, has not, have not (slang) |
| 75. | A female salmon |
| 76. | Queen of England 1702–14 |
| 77. | Loose flowing garment |
| 78. | Relationship diagram |
| 79. | Possessed |
| 80. | Person who annoys others by constantly finding fault |
|
| DOWN |
| 1. | 17th letter of the Greek alphabet |
| 2. | Or not |
| 3. | American Medical Association (abbr.) |
| 4. | Belonging to or on behalf of a specified person (esp. yourself) |
| 5. | Research Institute of America (abbr.) |
| 6. | 154 in Roman numerals |
| 7. | Baseball player Mel |
| 8. | Robbery |
| 9. | _ china |
| 10. | Lyric poems |
| 12. | Order of Saint Francis (abbr.) |
| 14. | A female yak |
| 20. | Spanish title |
| 21. | Adept person |
| 23. | Master of Engineering Administration (abbr.) |
| 25. | Celtic goddess who was the mother of the Tuatha De Danann |
| 26. | Film, stage and radio performer Massey (1912-1974) |
| 27. | A person who is older than you are |
| 29. | Is inclined (to) |
| 31. | Volcano in Mindanao |
| 34. | Compass dir. |
| 37. | Nervous spasm |
| 38. | Greek epic poem (attributed to Homer) describing the siege of Troy |
| 40. | Remove soap |
| 41. | At full speed |
| 43. | Hearing organ |
| 45. | Supplemented with great effort |
| 47. | Domesticated feline |
| 51. | International Chamber of Commerce (abbr.) |
| 53. | Thick or sticky substance |
| 54. | Compass dir. |
| 56. | Follow as a consequence or result |
| 59. | Component |
| 60. | Having or resembling wings |
| 62. | Chief or king in Benin or Nigeria |
| 63. | Hyperbolic tangent |
| 65. | Third month (abbr.) |
| 67. | Single |
| 69. | _ tizzy (2 wds.) |
| 70. | Diode which emits light from the p-n junction |
| 72. | Electrically charged atom |
| 73. | Basketball assoc. |
| 74. | A young ewe |
