| ACROSS |
| 1. | Charged atoms |
| 5. | Pacific Maritime Association (abbr.) |
| 8. | Research Institute of America (abbr.) |
| 11. | Indian titles of respect |
| 12. | United States Information Agency (abbr.) |
| 13. | It is |
| 14. | Tree or shrub in the Birch family |
| 16. | Capital of Latvia |
| 17. | Grand Old Party |
| 18. | To riddle |
| 19. | Small island |
| 22. | Virtual Memory System (abbr.) |
| 23. | The content of cognition |
| 24. | Master of Engineering Administration (abbr.) |
| 25. | A group of weasels |
| 26. | Affected manners intended to impress others |
| 28. | Greek goddess of the earth (variant) |
| 30. | Elected rep. |
| 32. | Disturbances |
| 34. | Animal reproductive body consisting of an ovum or embryo together with nutritive and protective envelopes |
| 35. | (biochemistry) Long linear polymer of nucleotides found in a cell |
| 37. | Nilotic language |
| 38. | Soviet premier 1918–24 |
| 41. | Compass dir. |
| 43. | Habitations of wild animals |
| 44. | Originally a stronghold captured by David (the 2nd king of the Israelites) |
| 45. | Seines |
| 47. | Single |
| 48. | Operatic vocal solo |
| 49. | Before (prefix) |
| 50. | Lake in Roros, Sor-Trondelag county, Norway |
| 51. | Teat (slang) |
| 54. | Flowery wreath |
| 55. | A disparaging term for an Italian, Spaniard, or Portuguese |
| 58. | Tarsus (plural) |
| 60. | Compass dir. |
| 61. | Son of Isaac |
| 62. | Tear apart |
| 63. | Two (Sp.) |
| 64. | And not |
| 65. | Wig |
|
| DOWN |
| 1. | Astrian river, tributary to the Danube |
| 2. | The wreath, or chaplet, surmounting or encircling the helmet of a knight |
| 3. | A group of pheasants |
| 4. | Compass dir. |
| 5. | 23rd letter of the Greek alphabet |
| 6. | Russian fighter aircraft |
| 7. | Auto club (abbr.) |
| 8. | Frustrating wastes of time |
| 9. | _ lemma (mathematics, stochastic calculus) |
| 10. | Viper |
| 12. | Use |
| 15. | Travel on an animal |
| 20. | Oceans |
| 21. | Member of a famous L.A. basketball team |
| 22. | Ancient city of Etruria north of modern-day Rome, Italy |
| 23. | _ tizzy (2 wds.) |
| 24. | Spoil |
| 25. | Signiories (variant) |
| 27. | Surprise greatly |
| 28. | Mixture with properties between those of a solution and fine suspension |
| 29. | Ripens |
| 31. | Compass dir. |
| 33. | Mayday |
| 36. | Slender Brazilian palm |
| 39. | City in the foothills of the Gold Country of California |
| 40. | Compass dir. |
| 42. | We are |
| 43. | Two long chains of nucleotides twisted into a double helix |
| 46. | Am not, is not, has not, have not (slang) |
| 49. | Monetary unit of Philippines |
| 50. | Right of Use (abbr.) |
| 51. | Woody plant |
| 52. | Is not |
| 53. | Periodic rise and fall of the sea level |
| 54. | Diode which emits light from the p-n junction |
| 55. | Lair |
| 56. | Volcano in Japan |
| 57. | Slender fish |
| 59. | Nonscientific branch of learning |