| ACROSS |
| 1. | Enemy |
| 4. | 4-wheeled motor vehicle |
| 7. | Nobel Price-winning Portuguese psychiatrist Moniz |
| 11. | Rotary motion of an object around its own axis |
| 13. | Double curve, resembling the letter S |
| 15. | Silent film actress Nazimova |
| 16. | Midwestern state in north central United States in the Great Lakes region |
| 17. | Perennial herbaceous plant in the rose family Rosaceae |
| 18. | Monetary unit of Brazil |
| 19. | Oblong piece of solid material |
| 22. | Yet |
| 24. | A young louse |
| 25. | Zeal |
| 28. | Research Institute of America (abbr.) |
| 30. | Electrically charged atom |
| 32. | Retirement account (abbr.) |
| 33. | Music discs |
| 34. | Personal Computers (abbr.) |
| 35. | A male wolf |
| 36. | Burn to charcoal |
| 39. | Avid follower |
| 42. | Cuckoo |
| 43. | Part |
| 44. | Small drink |
| 46. | _-fi |
| 48. | Am not, is not, has not, have not (slang) |
| 49. | Afternoon social gathering |
| 50. | Allow head to fall sleepily |
| 52. | Mouth or opening |
| 55. | Interstate Commerce Commission (abbr) |
| 56. | Simpleton |
| 57. | Not either |
| 58. | Portuguese money of account (variant) |
| 59. | A language that is deliberately created for a specific purpose |
| 61. | Non-commissioned officer (abbr.) |
| 64. | Member of the Shoshonean people of Utah and Colorado and New Mexico |
| 66. | To erase |
| 68. | A city of northeast Kyushu, Japan, east-northeast of Nagasaki |
| 71. | Soared |
| 75. | Matures |
| 76. | Series of steps to be carried out or goals to be accomplished |
| 77. | Edible starchy tuberous root |
| 78. | Connecting point |
| 79. | Take to court |
| 80. | Baking dish |
|
| DOWN |
| 1. | Away |
| 2. | Expression of pleasure, satisfaction, surprise, or great joy |
| 3. | Biblical high priest |
| 4. | Gear tooth |
| 5. | Grow older |
| 6. | Reuben's nickname |
| 7. | Hearing organ |
| 8. | American astronaut and politician John |
| 9. | Jai _ |
| 10. | Table seasoning |
| 12. | An easy return of a tennis ball in a high arc |
| 14. | Australian flightless bird |
| 20. | Curve |
| 21. | To free from |
| 23. | Nervous spasm |
| 25. | Cuban-born American model, actress and singer Guerra |
| 26. | Metal shackles |
| 27. | As yet unexplained, or too complicated to explain |
| 29. | Code for information exchange between computers |
| 31. | Open Software Foundation (abbr.) |
| 34. | Before (prefix) |
| 37. | A female salmon |
| 38. | 13-14th century defensive garment |
| 40. | Being in motion |
| 41. | Sibling's daughter |
| 43. | Writing tablet |
| 45. | A group of donkeys |
| 47. | _ tizzy (2 wds.) |
| 51. | Belonging to or on behalf of a specified person (esp. yourself) |
| 53. | Right of Use (abbr.) |
| 54. | Nonscientific branch of learning |
| 56. | Administered medicine |
| 59. | SW Asia republic |
| 60. | A disparaging term for an Italian, Spaniard, or Portuguese |
| 62. | Police officer (slang) |
| 63. | Lubricates |
| 65. | Newt |
| 67. | Compass dir. |
| 69. | The 19th letter of the Greek alphabet |
| 70. | A saturated hydrocarbon |
| 72. | Pet locale |
| 73. | Epoch |
| 74. | Monetary unit of South Korea |
