| ACROSS |
| 1. | United States Postal Service (abbr.) |
| 5. | Baseball player Mel |
| 8. | “Change” in Tahitian |
| 12. | What's left after other parts have been taken away |
| 13. | From |
| 14. | Regional Information Sharing System (abbr.) |
| 15. | Members of Hindu Caste from southern Indian state of Kerala |
| 17. | Polypeptide antibiotic |
| 20. | One more than two |
| 22. | Chief Executive Officer (abbr.) |
| 23. | Consume |
| 24. | Elects |
| 25. | Java container |
| 27. | Impair |
| 29. | Lipoprotein that transports cholesterol in the blood |
| 32. | Groovy apt. |
| 34. | Mouth or opening |
| 35. | First lady |
| 36. | To riddle |
| 38. | Dripping |
| 39. | Two long chains of nucleotides twisted into a double helix |
| 41. | Experiment locale |
| 43. | Distress signal |
| 45. | _ tizzy (2 wds.) |
| 47. | Compass dir. |
| 48. | Research Institute of America (abbr.) |
| 50. | A young louse |
| 51. | Nine, plus one |
| 52. | Adept person |
| 54. | River in Normandy, north-western France. |
| 57. | Arrange properly for use |
| 60. | An emergency procedure consisting of external cardiac massage and artificial respiration |
| 62. | Can I? |
| 63. | Inedible or poisonous agaric |
| 67. | Live dramatic performances |
| 71. | Southwest Nigerian state |
| 72. | Religious belief of African origin involving witchcraft and sorcery |
| 73. | Singles |
| 74. | Africa Soil Science Society (abbr.) |
| 75. | Small amount or degree |
| 76. | A home for chicks |
|
| DOWN |
| 1. | Large vase that usually has a pedestal or feet |
| 2. | Ocean |
| 3. | Air pressure measure (abbr.) |
| 4. | Empty completely |
| 5. | Often (poetically) |
| 6. | Attempt |
| 7. | Torque (variant) |
| 8. | Three (prefix) |
| 9. | Helper |
| 10. | United States Information Agency (abbr.) |
| 11. | Is not |
| 16. | Be seated |
| 18. | Original Equipment Manufacturer (abbr.) |
| 19. | Overturn; upset |
| 21. | Small island |
| 24. | Speaker |
| 26. | Slender fish |
| 27. | Cut the grass |
| 28. | Ancient Greek god of war |
| 30. | Movie disc |
| 31. | Soviet premier 1918–24 |
| 33. | Erase |
| 37. | Relaxation |
| 40. | Cuckoo |
| 42. | The inner or back room of a two-room cottage |
| 44. | Small drink |
| 46. | Smallest unit of an element |
| 49. | Arches |
| 53. | Elect |
| 55. | Strike |
| 56. | High-strength synthetic material |
| 57. | Portico |
| 58. | Immeasurably long periods of time |
| 59. | Bits |
| 61. | (botany) Usually underground organ that lacks buds or leaves or nodes |
| 64. | Two (Sp.) |
| 65. | Chief or king in Benin or Nigeria |
| 66. | Flaplike covering |
| 68. | One (Scot) |
| 69. | Affirmative reply |
| 70. | Supersonic Transport (abbr.) |