| ACROSS |
| 1. | Dinghy |
| 5. | Plant holder |
| 8. | Vertical spar for supporting sails |
| 12. | Horse sense |
| 13. | Quiet! |
| 14. | Small Philippine buffalo |
| 15. | Toward the future |
| 17. | Inedible or poisonous fungus with an umbrella-shaped body |
| 20. | It is so |
| 22. | Attempt to accomplish something |
| 23. | Compass dir. |
| 24. | Posted |
| 25. | _ tizzy (2 wds.) |
| 27. | Research Institute of America (abbr.) |
| 29. | Direct toward a target or goal |
| 32. | Certified Public Accountant (abbr.) |
| 34. | Lower and raise head in agreement |
| 35. | Non-commissioned officer (abbr.) |
| 36. | Chief or king in Benin or Nigeria |
| 38. | Black tropical American cuckoo |
| 39. | Eastern Standard Time (abbr.) |
| 41. | Sodium hydroxide |
| 43. | Curvy letter |
| 45. | Take to court |
| 47. | Snakelike fish |
| 48. | The 23rd letter of the Hebrew alphabet |
| 50. | Choose |
| 51. | _ Lanka |
| 52. | Writing tablet |
| 54. | A single undivided whole |
| 57. | Shallow baking pan |
| 60. | A female kangaroo |
| 62. | Indianapolis International Airport (abbr.) |
| 63. | Clearly or manifestly demonstrative |
| 67. | Wetness |
| 71. | Ache |
| 72. | A male domestic cat |
| 73. | Flexible conduit |
| 74. | Celtic language |
| 75. | Volcano in Pulau Sangihe |
| 76. | Double curve, resembling the letter S |
|
| DOWN |
| 1. | Two long chains of nucleotides twisted into a double helix |
| 2. | Expression of pleasure, satisfaction, surprise, or great joy |
| 3. | Sorrow |
| 4. | Belgian violinist, conductor, and composer Eugene |
| 5. | Pacific Standard Time (abbr.) |
| 6. | Expresson of surprise, comprehension, or mock astonishment |
| 7. | Not this but _ |
| 8. | Floor protector |
| 9. | At once, immediately (arch.) |
| 10. | Within a short period |
| 11. | Story |
| 16. | Lair |
| 18. | A female yak |
| 19. | Synchronize (abbr.) |
| 21. | Comedian Laurel of Laurel & Hardy |
| 24. | Someone who obtains pleasure from inflicting pain on others |
| 26. | Volcano in Mindanao |
| 27. | (biochemistry) Long linear polymer of nucleotides found in a cell |
| 28. | City in the foothills of the Gold Country of California |
| 30. | Frozen water |
| 31. | With motion or animation |
| 33. | Most capable |
| 37. | Town in the historic Nashoba Valley of Massachusetts |
| 40. | Heavy metal body, esp. the head of a power hammer |
| 42. | Biblical high priest |
| 44. | Plant excrement |
| 46. | Needle case |
| 49. | Notify of danger, potential harm, or risk |
| 53. | Two (Sp.) |
| 55. | Compass dir. |
| 56. | Potato state |
| 57. | Drink excessively |
| 58. | Astrian river, tributary to the Danube |
| 59. | Nuclear Threat Initiatives |
| 61. | A city of northeast Kyushu, Japan, east-northeast of Nagasaki |
| 64. | Compass dir. |
| 65. | Promise |
| 66. | Australian flightless bird |
| 68. | Coat; cloak |
| 69. | Compass dir. |
| 70. | To separate or throw off |
