| ACROSS |
| 1. | _ stream |
| 4. | Elected rep. |
| 7. | Queen of England 1702–14 |
| 11. | Greek god of love |
| 13. | South American Indian |
| 15. | Implement |
| 16. | Yard entry |
| 17. | Rend |
| 18. | Celtic language |
| 19. | Animal enclosure |
| 22. | Adept person |
| 24. | Beverage made from leaves |
| 25. | Open Software Foundation (abbr.) |
| 28. | Barrel |
| 30. | Expression of pleasure, satisfaction, surprise, or great joy |
| 32. | A female deer |
| 33. | Snakelike fish |
| 34. | Compass dir. |
| 35. | Everything |
| 36. | He sold his birthright |
| 39. | Italian singer-songwriter Filippo Neviani |
| 42. | Lipoprotein that transports cholesterol in the blood |
| 43. | Legendary creature resembling a tiny old man |
| 44. | Zeal |
| 46. | Boat paddle |
| 48. | Small Philippine buffalo |
| 49. | A saturated hydrocarbon |
| 50. | Large vase that usually has a pedestal or feet |
| 52. | A language that is deliberately created for a specific purpose |
| 55. | One of the 12 tribes of Israel |
| 56. | Belief that enlightenment can come through meditation and intuition rather than faith |
| 57. | Compass dir. |
| 58. | Curvy letter |
| 59. | A female animal or person |
| 61. | Keyboard modifier key |
| 64. | American Medical Association (abbr.) |
| 66. | Monetary unit of Turkey |
| 68. | Charged atoms |
| 71. | Practice fight |
| 75. | Scent |
| 76. | Otherwise |
| 77. | City of northwest Croatia on the Adriatic Sea |
| 78. | Trial |
| 79. | Newt |
| 80. | Plant excrement |
|
| DOWN |
| 1. | A young pike |
| 2. | Epoch |
| 3. | Small child |
| 4. | Be seated |
| 5. | Compass dir. |
| 6. | National Collegiate Athletic Association (abbr.) |
| 7. | Had dinner |
| 8. | _ pole |
| 9. | Olfactory organ |
| 10. | Ancient Greek colony of southern Italy near the Gulf of Salerno |
| 12. | Simplified Employee Pension (plan) (abbr.) |
| 14. | Curve |
| 20. | Make supply last |
| 21. | Born |
| 23. | Greek goddess of the dawn |
| 25. | Of the mouth |
| 26. | Small Italian coin worth a sou or a cent |
| 27. | Chap (slang) |
| 29. | American astronaut and politician John |
| 31. | Belonging to or on behalf of a specified person (esp. yourself) |
| 34. | Institute legal proceedings |
| 37. | "Barney Miller" actor Jack |
| 38. | At full speed |
| 40. | Elude |
| 41. | Monetary units of Papua New Guinea |
| 43. | Separate the seeds from cotton |
| 45. | Not women's |
| 47. | Regret |
| 51. | (biochemistry) Long linear polymer of nucleotides found in a cell |
| 53. | Two long chains of nucleotides twisted into a double helix |
| 54. | Original Equipment Manufacturer (abbr.) |
| 56. | Nothings |
| 59. | Narrow opening |
| 60. | A group of tigers |
| 62. | Falsehood |
| 63. | Lacquered or enameled metalware |
| 65. | Viper |
| 67. | Nonscientific branch of learning |
| 69. | National Science Foundation (abbr.) |
| 70. | Put into a specified state |
| 72. | Fluid product of inflammation |
| 73. | In the manner of |
| 74. | Reproach for some lapse or misdeed |
