| ACROSS |
| 1. | Label |
| 4. | Fast jet |
| 7. | Backtalk |
| 11. | The third and lowest division of the small intestine |
| 13. | Volcano in U.S.A. |
| 15. | West-central India city, east-southeast of Mumbai (Bombay) |
| 16. | To starve (Brit.) |
| 17. | Engineer (abbr.) |
| 18. | Operatic vocal solo |
| 19. | One (Scot) |
| 22. | Direct toward a target or goal |
| 24. | Uninterruptible Power Supply (abbr.) |
| 25. | A male domestic cat |
| 28. | Raised railways |
| 30. | Scottish cap |
| 32. | (biochemistry) Long linear polymer of nucleotides found in a cell |
| 33. | Sleep |
| 34. | Eastern Standard Time (abbr.) |
| 35. | Atmosphere |
| 36. | Court order |
| 39. | Increase |
| 42. | Group of languages of East Africa belonging to the Chari-Nile group |
| 43. | Relating to the nose |
| 44. | Mouth or opening |
| 46. | Make imperfect |
| 48. | A male horse |
| 49. | Monetary unit of Kyrgyzstan |
| 50. | Order of Saint Francis (abbr.) |
| 52. | Area sheltered from the wind |
| 55. | First lady |
| 56. | Third day of the wk. |
| 57. | A really long time |
| 58. | Lair |
| 59. | Auto |
| 61. | Keyboard key |
| 64. | Elected rep. |
| 66. | The opening section of a North Indian classical performance |
| 68. | A river of eastern Russia rising near Lake Baikal and flowing about 4,296 km (2,670 mi) northeast and north to the Laptev Sea |
| 71. | Toward the sea |
| 75. | Make new |
| 76. | A male goose |
| 77. | Abrupt rush of wind |
| 78. | Teenager |
| 79. | Observe |
| 80. | Compass dir. |
|
| DOWN |
| 1. | Nervous spasm |
| 2. | Everything |
| 3. | Unit of force equal to gravity |
| 4. | A female animal or person |
| 5. | Manchild |
| 6. | Ancient Roman robe |
| 7. | Health resort |
| 8. | Gold (Symbol: Au) |
| 9. | Sever or remove by pinching or nipping |
| 10. | Oceans |
| 12. | American Medical Association (abbr.) |
| 14. | A female yak |
| 20. | Italian singer-songwriter Filippo Neviani |
| 21. | Biblical high priest |
| 23. | Mountains (abbr.) |
| 25. | Town in Pulwama district in the Indian state of Jammu and Kashmir |
| 26. | Containing a positively charged radical (suffix) |
| 27. | Volcano in North Island |
| 29. | Small fatty European fish |
| 31. | _ moment's notice (2 wds.) |
| 34. | Snakelike fish |
| 37. | Volcano in Japan |
| 38. | Dipping utensil |
| 40. | Administered medicine |
| 41. | A group of rabbits |
| 43. | National Science Foundation (abbr.) |
| 45. | So be it |
| 47. | Radius Of Uncertainty (abbr.) |
| 51. | Arrange properly for use |
| 53. | Greek goddess of the dawn |
| 54. | Compass dir. |
| 56. | Exchange |
| 59. | Draw slowly or heavily |
| 60. | Toward shelter |
| 62. | Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord |
| 63. | Stakes |
| 65. | Person who annoys others by constantly finding fault |
| 67. | Passive Optical Network (abbr.) |
| 69. | Born |
| 70. | Mature |
| 72. | Institute legal proceedings |
| 73. | Double-curved letter |
| 74. | Had dinner |