| ACROSS |
| 1. | A saturated hydrocarbon |
| 4. | Cartoonist voice _ Blanc |
| 7. | Confront |
| 11. | Greater amount |
| 13. | SW Saudi Arabia district |
| 15. | Queen of England 1702–14 |
| 16. | Ancient river in northeast Turkey |
| 17. | French philosopher Descartes |
| 18. | Event that recurs at intervals |
| 19. | Beverage made from leaves |
| 22. | Last letter of the English alphabet |
| 24. | Spanish title |
| 25. | Madame (abbr.) |
| 28. | Mouth edge |
| 30. | Virtual Memory System (abbr.) |
| 32. | Atmosphere |
| 33. | _ tizzy (2 wds.) |
| 34. | Ocean |
| 35. | Pacific Maritime Association (abbr.) |
| 36. | Oceans |
| 39. | Before (prefix) |
| 42. | Be seated |
| 43. | Showing deterioration from age |
| 44. | Naughty child |
| 46. | Right of Use (abbr.) |
| 48. | Australian parrot (variant) |
| 49. | Pakistan head of state, July 1977 - August 1988 |
| 50. | Marina Del _, California |
| 52. | At this time |
| 55. | Everything |
| 56. | Compass dir. |
| 57. | Curvy letter |
| 58. | Potassium hydroxide |
| 59. | _-fi |
| 61. | Lipoprotein that transports cholesterol in the blood |
| 64. | Belonging to or on behalf of a specified person (esp. yourself) |
| 66. | Ancient Greek god of war |
| 68. | National Aeronautics and Space Administration (abbr.) |
| 71. | Oregon Treasure Trail Society (abbr.) |
| 75. | Technical |
| 76. | Afresh |
| 77. | Raised platform |
| 78. | Institute of Electrical and Electronics Engineers (abbr.) |
| 79. | Unit of force equal to gravity |
| 80. | _ stream |
|
| DOWN |
| 1. | American Medical Association (abbr.) |
| 2. | And not |
| 3. | Period |
| 4. | Spoil |
| 5. | Compass dir. |
| 6. | A city of northern Austria on the Danube River west of Vienna |
| 7. | Floor covering |
| 8. | City of north-central Oklahoma north-northwest of Oklahoma City (plural) |
| 9. | Inside; within (prefix) |
| 10. | Teenager |
| 12. | Eastern Standard Time (abbr.) |
| 14. | To sift |
| 20. | Biblical high priest |
| 21. | The 18th letter of the Arabic alphabet |
| 23. | First lady |
| 25. | Atlas contents |
| 26. | (Norse mythology) Giant who lives in the roots of Yggdrasil and guards the well of wisdom |
| 27. | Greek mythological Muse of lyric poetry and mime |
| 29. | City of southwest Colombia near the Ecuadorian border |
| 31. | Atlas unit |
| 34. | Compass dir. |
| 37. | Hearing organ |
| 38. | Arrange so as to be parallel or straight |
| 40. | Philippine national hero and writer Jose |
| 41. | Poet Dickinson |
| 43. | Mischievous |
| 45. | Light colored |
| 47. | Large vase that usually has a pedestal or feet |
| 51. | Snakelike fish |
| 53. | Bear (Spanish) |
| 54. | Compass dir. |
| 56. | Sibling's daughter |
| 59. | Suttee (variant) |
| 60. | North American Indian people of Ontario, Manitoba, Saskatchewan, and Montana |
| 62. | Two long chains of nucleotides twisted into a double helix |
| 63. | Austrian-born American filmmaker Fritz |
| 65. | Lower and raise head in agreement |
| 67. | A female animal or person |
| 69. | Observe |
| 70. | Deep reverence |
| 72. | _ Mahal |
| 73. | Neckwear |
| 74. | Fast jet |